Enhanced compatibility and initial stability of Ti6Al4V alloy orthodontic miniscrews subjected to anodization, cyclic precalcification, and heat treatment
오은주, Nguyen Thuy-Duong T., 이승엽, 전영미, 배태성, Kim Jong-Gee,
소속 상세정보
오은주 ( Oh Eun-Ju ) - Sun Dental Hospital
( Nguyen Thuy-Duong T. ) - Chonbuk National University School of Dentistry Department of Dental Biomaterials
이승엽 ( Lee Seung-Youp ) - Chonbuk National University School of Dentistry Department of Orthodontics
전영미 ( Jeon Young-Mi ) - Chonbuk National University School of Dentistry Department of Orthodontics
배태성 ( Bae Tae-Sung ) - Chonbuk National University School of Dentistry Department of Dental Biomaterials
( Kim Jong-Gee ) - Chonbuk National University School of Dentistry Department of Orthodontics
KMID : 0361920140440050246
Abstract
Objective: To evaluate the bioactivity, and the biomechanical and bone-regenerative properties of Ti6Al4V miniscrews subjected to anodization, cyclic precalcification, and heat treatment (APH treatment) and their potential clinical use.
Methods: The surfaces of Ti6Al4V alloys were modified by APH treatment. Bioactivity was assessed after immersion in simulated body fluid for 3 days. The hydrophilicity and the roughness of APH-treated surfaces were compared with those of untreated (UT) and anodized and heat-treated (AH) samples. For in vivo tests, 32 miniscrews (16 UT and 16 APH) were inserted into 16 Wistar rats, one UT and one APH-treated miniscrew in either tibia. The miniscrews were extracted after 3 and 6 weeks and their osseointegration (n = 8 for each time point and group) was investigated by surface and histological analyses and removal torque measurements.
Results: APH treatment formed a dense surface array of nanotubular TiO2 layer covered with a compact apatite-like film. APH-treated samples showed better bioactivity and biocompatibility compared with UT and AH samples. In vivo, APH-treated miniscrews showed higher removal torque and bone-to-implant contact than did UT miniscrews, after both 3 and 6 weeks (p < 0.05). Also, early deposition of densely mineralized bone around APH-treated miniscrews was observed, implying good bonding to the treated surface.
Conclusions: APH treatment enhanced the bioactivity, and the biomechanical and bone regenerative properties of the Ti6Al4V alloy miniscrews. The enhanced initial stability afforded should be valuable in orthodontic applications.
키워드
Orthodontic mini-implant; Stability; Biocompatibility; Surface treatment
원문 및 링크아웃 정보
등재저널 정보